Virulence factors of Burkholderia cepacia

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Virulence factors of Burkholderia cepacia.

Originally named following its identification as a cause of soft rot in onions, Burkholderia cepacia has also been known as Pseudomonas multivorans and Pseudomonas kingae [1,2], and until most recently, as Pseudomonas cepacia [3]. A proposal for the transfer of 7 species of the genus Pseudomonas RNA Homology group II to a new genus Burkholderia with the type-species Burkholderia cepacia has bee...

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Burkholderia cepacia Complex: Emerging Multihost Pathogens Equipped with a Wide Range of Virulence Factors and Determinants

The Burkholderia cepacia complex (Bcc) comprises at least 17 closely-related species of the beta-proteobacteria subdivision, widely distributed in natural and man-made inhabitats. Bcc bacteria are endowed with an extraordinary metabolic diversity and emerged in the 1980s as life-threatening and difficult-to-treat pathogens among patients suffering from cystic fibrosis. More recently, these bact...

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Commercial use of Burkholderia cepacia.

Letters toxicity, no antidiphtheria serum was administered. The patient became well and was discharged on day 4. In the first case, a throat culture could not be done because the patient had already received local antiseptic paint. However, the diagnosis was clinically consistent with classic diphtheria with features of toxicity. In the second case, diphtheria was suspected only after bacteriol...

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Burkholderia cepacia is an important pathogen in patients with cystic fibrosis (CF) and much is now known of its epidemiology. In contrast, its virulence mechanisms are poorly understood. The lipopolysaccharide (LPS) of B. cepacia, a well-recognised virulence factor of other gram-negative bacteria, is known to be strongly endotoxic in vitro. The aim of this study was to observe if there were an...

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ژورنال

عنوان ژورنال: FEMS Immunology and Medical Microbiology

سال: 1994

ISSN: 0928-8244

DOI: 10.1016/0928-8244(94)90033-7